Principal Clinical Scientist (AI Training)

About The Role
What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI reasons about medicine, data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential challenges in AI development: ensuring that AI systems trained on clinical data actually understand it the way regulators, researchers, and clinicians do. This is a fully remote, versátil contract role built for experienced clinical scientists who want to work at the frontier of AI and biomedical research — on their own terms.
• Organization: Alignerr
• Type: Hourly Contract
•

Location:
Remote
• Commitment: 10–40 hours/week

What You'll Do
• Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations
• Provide expert, structured feedback that directly improves how AI models reason about clinical evidence, trial methodology, and outcomes
• Flag gaps, inconsistencies, or methodological errors in AI-generated clinical content
• Work independently and asynchronously — fully on your own schedule Who You Are




• Senior-level experience designing clinical trial protocols for regulatory submission — you've done this at a high level in the real world
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold AI-generated content to the same standards you'd apply to a real submission
• Clear and precise written communicator who can articulate complex scientific reasoning in structured feedback Nice to Have
• Prior experience with data annotation, data quality assurance, or evaluation systems
• Background in regulatory affairs, clinical operations, or medical writing
• Familiarity with AI tools or scientific evaluation workflows
• Experience working across therapeutic areas or with international regulatory submissions Why Join Us
• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence — at scale
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, high-impact work
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Ciudad de México)
🏢 Alignerr
📍 Ciudad de México