In the Leibniz Institute of Plant Biochemistry, the independent research group Receptor Biochemistry invites applications for aPostdoctoral Researcher Position— N-terminomics and Protease Degradomics (m/f/d) (11/2026)How does proteolytic regulation control plant plasma-membrane receptor function and plant immune responses?The plant plasma membrane is a dynamic hub for nutrient uptake, pathogen detection and stress signalling, anchored by surface receptors. In animals, proteolytic cleavage of membrane proteins is a major regulatory mechanism in immunity. In plants, its role remains largely unexplored.FRONTERA, funded by the European Research Council through an ERC Starting Grant, sets out to close that gap. The project combines chemoproteomics, cell biology, protease biochemistry and genetics, and looks at both sides of the process: the proteases that cut, and the substrates they act on. It is curiosity-driven research with a long view towards crop resilience and sustainable agriculture.You will lead the degradomics side of FRONTERA, establishing terminomics in our system to identify cleaved substrates and map where they are cut.Establish and optimise a terminomics workflow for plant samplesIdentify protease substrates and determine cleavage sites, and follow how processing changes during immune responsesDevelop the data analysis alongside the wet-lab method, working with our in-house mass spectrometry facilityValidate candidate cleavage events biochemically and relate them to immune signalling, in collaboration with the teamCo-supervise a doctoral researcherPresent and publish your scientific dataYour profileA doctoral degree in biochemistry, analytical chemistry, molecular biology, plant science or a closely related field. If your thesis is submitted but not yet defended by the start date, please apply and tell us your timeline.Substantial hands-on experience in MS-based proteomics, working independently from sample preparation through to data analysisInterest in mentoring a doctoral researcherExcellent English language skills,



written and spoken. German is not required.Protease biochemistryQuantitative proteomics with isobaric or metabolic labellingScripting for proteomics data analysis (R, Python), search engines, downstream statisticsExperience in adapting or establishing proteomics workflows for new sample types or questions. Tell us about one in your cover letter.Work with plant materialSupervision or teaching experienceRead the second list as a description of the project, not a test. In particular, prior N-terminomics experience is not required. Candidates who would do this job well routinely talk themselves out of applying because they match four points instead of seven. Tell us in your cover letter what you would need to learn.Modern Working ConditionsComprehensive introduction to work techniques and a modern research environment with state-of-the-art equipment and up-to-date softwareCareer DevelopmentTargeted training opportunities and access to a specialized library with electronic resources and quiet workspacesCompensation & SecurityClassification according to TV-L including annual bonus, pension scheme (VBL), health offers, and discounted canteen mealsIdeal Working EnvironmentA varied and inspiring workplace in an international setting at a leading scientific and innovation hubTeam Spirit and Leadership CultureAn open culture that strengthens teamwork, enables career networking, and promotes your research skills.Work-Life BalanceFlexible working models, remote work options, and 30 days of annual leave – for a balanced work-life experience.About usThe Independent Research Group Receptor Biochemistry, led by Dr. Mariana Schuster,



is dedicated to understanding and engineering the molecular decisions that determine whether a plant gets sick, focusing on the proteases deployed by plants and pathogens and the proteins they cut. We are small, international and deliberately interdisciplinary. People here come from plant science, biochemistry, chemistry and computational backgrounds, and much of the useful thinking happens in the conversations between them.The IPB is a non-university research institute of the Leibniz Association on the Weinberg Campus of Martin Luther University Halle-Wittenberg, a foundation under public law under the direct supervision of the state of Saxony-Anhalt. Around 200 people work here, including about 40 doctoral researchers, across four scientific departments and two independent research groups. Research at the IPB aims to understand the (bio)chemical basis of plant resilience and performance in challenging environments related to climate change. The IPB offers excellent research facilities and state-of-the-art infrastructure, including in-house mass spectrometry. More at ipb-halle.De.Halle (Saale) is a green, walkable city with a large student population, low living costs by German standards, and fast connections to Leipzig and Berlin.Contact personDr. Mariana SchusterHead of Research GroupTelefon:[email protected] für Pflanzenbiochemie (IPB)Weinberg 306120 Halle (Saale)The Leibniz Institute of Plant Biochemistry is committed to equal opportunities, diversity and promoting a healthy work-life balance, and has been awarded the "Total E-Quality" rating for its efforts in this area. The IPB is also a member of the nationwide "Success Factor Family" corporate network and the Diversity Charter. Applications from severely disabled persons or applicants of equivalent status are expressly welcome. Further information on family friendliness, equal opportunities and diversity can be found at: www.Ipb-halle.De/institut#J-18808-Ljbffr

📌 Postdoctoral Researcher Position— N-Terminomics And Protease Degradomics (Frontera)
🏢 Ipb Halle
📍 Frontera