Principal Clinical Scientist (AI Training) About The Role What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI reasons about medicine, data, and patient outcomes? We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential challenges in AI development: ensuring that AI systems trained on clinical data actually understand it the way regulators, researchers, and clinicians do. This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the frontier of AI and biomedical research — on their own terms.

Organization: Alignerr

Type: Hourly Contract

Location: Remote

Commitment: 10–40 hours/week What You'll Do Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training

Interpret and audit clinical trial results for accuracy, consistency, and alignment with regulatory standards

Evaluate AI-generated clinical analyses for scientific soundness and compliance with FDA, EMA, or equivalent agency expectations

Provide expert, structured feedback that directly improves how AI models reason about clinical evidence, trial methodology, and outcomes

Flag gaps, inconsistencies, or methodological errors in AI-generated clinical content





Work independently and asynchronously — fully on your own schedule Who You Are Senior-level experience designing clinical trial protocols for regulatory submission — you've done this at a high level in the real world

Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies

Strong grounding in clinical research methodology, biostatistics, or translational science

Naturally rigorous and detail-oriented — you hold AI-generated content to the same standards you'd apply to a real submission

Clear and precise written communicator who can articulate complex scientific reasoning in structured feedback Nice to Have Prior experience with data annotation, data quality assurance, or evaluation systems

Background in regulatory affairs, clinical operations, or medical writing

Familiarity with AI tools or scientific evaluation workflows

Experience working across therapeutic areas or with international regulatory submissions Why Join Us Work directly on frontier AI systems that are reshaping clinical and biomedical research

Influence how AI understands, evaluates, and reasons about real-world clinical evidence — at scale

Fully remote and adaptable — work when and where it suits you

Freelance autonomy with the structure of meaningful, high-impact work

Collaborate with world-leading AI research teams and labs

Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Ciudad de México)
🏢 Alignerr
📍 Ciudad de México